Karume received his J.D. from Brooklyn Law School in 2014, where he was an Edward V. Sparer Public Interest Fellow, Associate Research Editor for the Journal of Law & Policy, and a member of the Brooklyn Law School Moot Court Honor Society, Trial Division. Karume interned his first summer at the Legal Aid Society, Employment Law Unit, and interned his second summer at The Bronx Defenders. While in law school, Karume was the Vice President of Alumni Relations for the Black Law Students Association and an executive board member of both Brooklyn Law Students for the Public Interest (BLSPI) and the National Lawyers Guild. Prior to law school, Karume worked as a grassroots organizer, first representing unionized healthcare workers, and later as a community organizer in South Central Los Angeles. Karume holds a B.A. in African American Studies with a concentration in Psychology from UCLA.